UBE3D

Across TCGA cell cohorts, UBE3D RNA expression is significantly associated with the go_rna of many other GO terms, with 4,763 significant associations in total. BONE shows the largest number of these associations.

The most reproducible UBE3D-associated GO terms across cancer lineages are 'de novo' IMP biosynthetic process, Mitochondrial RNA metabolic process, and Quinone biosynthetic process. Each is linked with UBE3D in more than 14 cancer types. Because this analysis shows association rather than direction, both UBE3D-to-partner and partner-to-UBE3D results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, 'de novo' IMP biosynthetic process grouped by UBE3D-low versus UBE3D-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (UBE3D→partner) and Y-score (partner→UBE3D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	'de novo' IMP biosynthetic process →	+0.130	+0.574	<.001	.002	3	15
BONE	Mitochondrial RNA metabolic process →	+0.091	+1.200	.001	.002	3	14
BONE	Quinone biosynthetic process →	+0.111	+1.775	<.001	<.001	3	13
BONE	DNA replication initiation →	+0.164	+1.565	.003	<.001	3	13
BONE	DNA-templated transcription termination →	+0.103	+1.220	<.001	.005	3	13
BONE	tRNA metabolic process →	+0.076	+1.568	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,763 associations by consensus.

'de novo' IMP biosynthetic process by UBE3D expression — OVARY

Explore this box plot interactively →