UBE3B

Across TCGA patient cohorts, UBE3B RNA expression is significantly associated with the protein abundance of many other proteins, with 12,662 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible UBE3B-associated proteins across cancer lineages are SART3, WRNIP1, and CRELD2. Each is linked with UBE3B in more than 5 cancer types. Because this analysis shows association rather than direction, both UBE3B-to-partner and partner-to-UBE3B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, UBE3B versus SART3 in LSCC, with a Pearson correlation of 0.55.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (UBE3B→partner) and Y-score (partner→UBE3B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SART3 →	+0.245	+0.364	<.001	<.001	3	6
LUAD	WRNIP1 →	+0.277	+0.318	.002	<.001	3	5
LSCC	CRELD2 →	-0.510	-0.380	<.001	<.001	3	5
HNSC	C1orf35 →	+0.357	+0.665	.005	.007	3	5
BRCA	MICALL1 →	-0.309	-0.365	.005	.003	3	4
PDAC	SNRPD2 →	+0.169	+0.321	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,662 associations by consensus.

UBE3B vs SART3 — LSCC

Explore this scatter interactively →