UBE3AP2

Across TCGA patient cohorts, UBE3AP2 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,624 significant associations in total. STAD shows the largest number of these associations.

The most reproducible UBE3AP2-associated GO terms across cancer lineages are RNA destabilization, Positive regulation of mRNA metabolic process, and Transcription by RNA polymerase III. Each is linked with UBE3AP2 in more than 20 cancer types. Because this analysis shows association rather than direction, both UBE3AP2-to-partner and partner-to-UBE3AP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA destabilization grouped by UBE3AP2-low versus UBE3AP2-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (UBE3AP2→partner) and Y-score (partner→UBE3AP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	RNA destabilization →	+0.057	+0.108	<.001	<.001	3	21
STAD	Positive regulation of mRNA metabolic process →	+0.065	+0.107	<.001	<.001	3	21
STAD	Transcription by RNA polymerase III →	+0.061	+0.114	<.001	<.001	3	21
STAD	Positive regulation of telomere maintenance via telomere lengthening →	+0.065	+0.100	<.001	<.001	3	20
STAD	Regulation of ubiquitin-dependent protein catabolic process →	+0.068	+0.099	<.001	<.001	3	20
STAD	RNA polymerase II preinitiation complex assembly →	+0.061	+0.106	<.001	<.001	3	20

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,624 associations by consensus.

RNA destabilization by UBE3AP2 expression — STAD

Explore this box plot interactively →