UBE3AP2

Across TCGA pan-cancer cohorts, UBE3AP2 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of UBE3AP2’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where UBE3AP2 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types UBE3AP2 is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.

COAD, THCA, and KIRC are the cancer types where UBE3AP2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in UBE3AP2 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Female	IV	+0.084	.003	6	view →
THCA	Male	II,III,IV	−0.033	.001	3	view →
KIRC	All	All	+0.008	.008	2	view →
LUSC	Female	All	+0.022	.020	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

UBE3AP2–COAD

Open the COAD breakdown →