UBE2W

Across TCGA cell cohorts, UBE2W mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible UBE2W-associated genes across cancer lineages are LHCGR, GPR6, and OR10W1. Each is linked with UBE2W in more than 1 cancer types. Because this analysis shows association rather than direction, both UBE2W-to-partner and partner-to-UBE2W results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LHCGR grouped by UBE2W-low versus UBE2W-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UBE2W→partner) and Y-score (partner→UBE2W) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	LHCGR →	+0.050	+4.467	<.001	.004	3	1
LARGE_INTESTINE	GPR6 →	+0.010	+5.022	<.001	.002	3	1
LARGE_INTESTINE	OR10W1 →	+0.024	+5.562	<.001	<.001	3	1
LARGE_INTESTINE	PHOX2B →	+0.047	+4.362	<.001	.005	1	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

LHCGR by UBE2W expression — LARGE_INTESTINE

Explore this box plot interactively →