UBE2W

Across TCGA cell cohorts, UBE2W mutation is significantly associated with the mutation status of many other genes, with 534 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible UBE2W-associated genes across cancer lineages are CHERP, L2HGDH, and KIF9. Each is linked with UBE2W in more than 1 cancer types. Because this analysis shows association rather than direction, both UBE2W-to-partner and partner-to-UBE2W results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CHERP grouped by UBE2W-low versus UBE2W-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UBE2W→partner) and Y-score (partner→UBE2W) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	CHERP →	+2.865	+4.217	.007	.007	1	1
LARGE_INTESTINE	L2HGDH →	+4.087	+5.044	.001	.001	1	1
LARGE_INTESTINE	KIF9 →	+5.087	+4.523	.006	.006	1	1
LARGE_INTESTINE	TASP1 →	+3.087	+4.392	.005	.005	1	1
LARGE_INTESTINE	CMTM1 →	+5.087	+4.523	.006	.006	1	1
LARGE_INTESTINE	CHRD →	+3.087	+4.392	.005	.005	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 534 associations by consensus.

CHERP by UBE2W expression — LARGE_INTESTINE

Explore this box plot interactively →