UBE2V2

Across TCGA pan-cancer cohorts, UBE2V2 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated UBE2V2 data layer compared with 26 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher UBE2V2 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated UBE2V2 expression acts as an unfavorable survival marker, although some lineages such as LSCC show a favorable association.

LSCC, PDAC, and HNSC are the cancer types where UBE2V2 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	OS	Tertile	All	0.958	0.650	.001	19	view →
PDAC	DFS	Quartile	III,IV	0.351	1.000	.005	7	view →
HNSC	DFS	Tertile	IV	0.477	0.736	.031	1	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

UBE2V2–LSCC (OS)

Open the LSCC breakdown →