UBE2V1

Across TCGA cell cohorts, UBE2V1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,410 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible UBE2V1-associated GO terms across cancer lineages are Protein linear deubiquitination, Mitotic centrosome separation, and IRE1-mediated unfolded protein response. Each is linked with UBE2V1 in more than 11 cancer types. Because this analysis shows association rather than direction, both UBE2V1-to-partner and partner-to-UBE2V1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein linear deubiquitination grouped by UBE2V1-low versus UBE2V1-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (UBE2V1→partner) and Y-score (partner→UBE2V1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Protein linear deubiquitination →	+0.087	+0.629	<.001	<.001	3	12
BREAST	Mitotic centrosome separation →	+0.119	+0.563	.004	.002	3	11
STOMACH	IRE1-mediated unfolded protein response →	+0.181	+0.822	<.001	<.001	3	10
BREAST	Insulin receptor recycling →	+0.233	+1.000	<.001	<.001	3	10
STOMACH	Response to oscillatory fluid shear stress →	+0.218	+1.017	.001	<.001	3	10
STOMACH	Cellular response to oscillatory fluid shear stress →	+0.218	+1.017	.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,410 associations by consensus.

Protein linear deubiquitination by UBE2V1 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →