UBE2V1

Across TCGA pan-cancer cohorts, UBE2V1 RNA is linked to patient survival in 30 of 34 cancer types, making it the most broadly survival-associated UBE2V1 data layer compared with 3 for mass-spec protein.

The strongest signal is observed in mesothelioma (MESO), where higher UBE2V1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated UBE2V1 expression acts as an unfavorable survival marker, although some lineages such as UCS and GBM show a favorable association.

MESO, HNSC, and CESC are the cancer types where UBE2V1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	DFS	Tertile	All	0.238	0.521	<.001	102	view →
HNSC	OS	Median	II,III,IV	0.679	0.807	<.001	57	view →
CESC	OS	Quartile	All	0.485	0.787	<.001	50	view →
ACC	OS	Quartile	All	0.238	0.879	<.001	48	view →
LIHC	DFS	Quartile	All	0.397	0.597	<.001	37	view →
BLCA	DFS	Tertile	All	0.203	0.577	<.001	36	view →
UCS	DFS	Median	IV	0.952	0.367	.001	36	view →
LGG	OS	Median	All	0.738	0.944	<.001	35	view →
UVM	OS	Quartile	III,IV	0.469	1.000	.005	31	view →
LUSC	DFS	Tertile	II,III,IV	0.584	0.866	.006	28	view →
KIRP	DFS	Tertile	All	0.578	0.725	.003	28	view →
UCEC	DFS	Quartile	All	0.604	0.887	<.001	28	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 30 lineages.

UBE2V1–MESO (DFS)

Open the MESO breakdown →