UBE2U

Across TCGA cell cohorts, UBE2U RNA expression is significantly associated with the go_rna of many other GO terms, with 148 significant associations in total. LUNG_NSCLC_LUSC shows the largest number of these associations.

The most reproducible UBE2U-associated GO terms across cancer lineages are Positive regulation of SMAD protein signal transduction, Regulation of T-helper 17 cell differentiation, and Deoxyribonucleotide biosynthetic process. Each is linked with UBE2U in more than 2 cancer types. Because this analysis shows association rather than direction, both UBE2U-to-partner and partner-to-UBE2U results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of SMAD protein signal transduction grouped by UBE2U-low versus UBE2U-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (UBE2U→partner) and Y-score (partner→UBE2U) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Positive regulation of SMAD protein signal transduction →	+0.061	+0.055	.001	.008	3	3
SOFT_TISSUE	Regulation of T-helper 17 cell differentiation →	+0.105	+0.127	<.001	.008	2	3
OVARY	Deoxyribonucleotide biosynthetic process →	-0.094	-0.053	<.001	.001	3	2
LUNG_NSCLC_LUSC	Ribonucleoside biosynthetic process →	+0.189	+0.043	.001	.004	3	2
LUNG_NSCLC_LUSC	Retinal metabolic process →	-0.279	-0.052	<.001	.008	3	2
LUNG_NSCLC_LUSC	Positive regulation of macrophage activation →	+0.218	+0.043	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 148 associations by consensus.

Positive regulation of SMAD protein signal transduction by UBE2U expression — STOMACH

Explore this box plot interactively →