Across TCGA patient cohorts, UBE2QL1 mutation is significantly associated with the RNA expression of many other genes, with 55 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible UBE2QL1-associated genes across cancer lineages are MIR6130, OR4K16P, and RNU6-283P. Each is linked with UBE2QL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both UBE2QL1-to-partner and partner-to-UBE2QL1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UBE2QL1→partner) and Y-score (partner→UBE2QL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MIR6130 →	+0.333	+8.471	<.001	.005	3	1
BRCA	OR4K16P →	+0.044	+7.731	.001	.009	3	1
ESCA	RNU6-283P →	+0.305	+5.681	<.001	.003	3	1
ESCA	RNU6-675P →	+0.312	+5.450	<.001	.004	3	1
ESCA	MTCYBP2 →	+0.229	+5.068	<.001	.008	3	1
ESCA	MIR1185-2 →	+0.512	+5.681	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 55 associations by consensus.

Exploration

UBE2QL1 survival (RNA) · tumor vs normal (RNA) · all UBE2QL1 data types