Across TCGA pan-cancer cohorts, UBE2QL1 RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of UBE2QL1’s most consistent transcriptional readouts.
The strongest signal is observed in colon adenocarcinoma (COAD), where UBE2QL1 RNA is repressed in tumor relative to normal tissue. In most cancer types UBE2QL1 is over-expressed in tumor, although a few such as COAD and KIRP show the opposite, repressed pattern.
COAD, KIRP, and STAD are the cancer types where UBE2QL1 tumor–normal differential expression is most reproducible.
RNA tumor vs normal associations by lineage
Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in UBE2QL1 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.