UBE2NP1

Across TCGA patient cohorts, UBE2NP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,773 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible UBE2NP1-associated GO terms across cancer lineages are Interstrand cross-link repair, Maturation of 5.8S rRNA, and Endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Each is linked with UBE2NP1 in more than 13 cancer types. Because this analysis shows association rather than direction, both UBE2NP1-to-partner and partner-to-UBE2NP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Interstrand cross-link repair grouped by UBE2NP1-low versus UBE2NP1-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (UBE2NP1→partner) and Y-score (partner→UBE2NP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Interstrand cross-link repair →	+0.059	+0.243	<.001	.001	3	14
ESCA	Maturation of 5.8S rRNA →	+0.067	+0.211	<.001	<.001	3	14
DLBC	Endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	+0.059	+0.184	<.001	<.001	3	13
ESCA	DNA replication →	+0.064	+0.233	<.001	<.001	3	13
ESCA	DNA-templated DNA replication →	+0.078	+0.264	<.001	<.001	3	13
DLBC	Transcription by RNA polymerase III →	+0.063	+0.311	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,773 associations by consensus.

Interstrand cross-link repair by UBE2NP1 expression — ESCA

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