ubiquitin conjugating enzyme E2 N pseudogene 1Genealiases: []
Q-omics provides the consensus-scored UBE2NP1 profile across patient tissues and cancer cell-line models. UBE2NP1 expression is associated with patient survival in 14 of 34 cancer types, with the highest sampling consensus in THCA. Among the 18 cancer types available for tumor–normal comparison, UBE2NP1 is differentially expressed in 8, with the highest sampling consensus in COAD. Additionally, UBE2NP1 RNA expression shows 5,773 significant pathway-activity associations, with the highest sampling consensus in UCEC. Together, these results highlight THCA, COAD, and UCEC as cancer lineages where UBE2NP1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for UBE2NP1 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes UBE2NP1 survival associations across molecular data types. UBE2NP1 RNA expression shows survival associations in the most cancer types (14). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible UBE2NP1 RNA expression–survival associations across cancer types. High UBE2NP1 expression shows unfavorable associations in THCA, KICH, MESO and LIHC, but favorable associations in UCEC and READ. The THCA Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .007). Together, the overview and detailed table identify THCA as the clearest survival context for UBE2NP1 RNA expression.
This table summarizes UBE2NP1 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 8. The strongest signals are observed in COAD for RNA.
This table ranks reproducible tumor–normal expression differences for UBE2NP1. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. UBE2NP1 shows lower tumor expression in PAAD and READ and higher tumor expression in COAD, BRCA, UCEC and PRAD. The COAD box plot shows higher UBE2NP1 RNA expression in tumor versus normal tissue (log2 FC = +0.231, t-test p < 0.001).
This table shows molecular features associated with UBE2NP1 in patient tissues and cancer cell lines. In patient samples, UBE2NP1 shows the broadest associations at the RNA and protein expression levels, with UCEC recurring as the lineage with the largest associated feature set.
