UBE2N

Across TCGA patient cohorts, UBE2N protein abundance is significantly associated with the RNA expression of many other genes, with 10,854 significant associations in total. GBM shows the largest number of these associations.

The most reproducible UBE2N-associated genes across cancer lineages are LTA4H, DPYD, and C12orf73. Each is linked with UBE2N in more than 3 cancer types. Because this analysis shows association rather than direction, both UBE2N-to-partner and partner-to-UBE2N results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, UBE2N versus LTA4H in BRCA, with a Pearson correlation of 0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UBE2N→partner) and Y-score (partner→UBE2N) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	LTA4H →	+0.499	+0.332	<.001	<.001	3	4
GBM	DPYD →	-1.201	-0.201	<.001	<.001	3	4
OV	C12orf73 →	+0.484	+0.281	<.001	.001	3	4
PDAC	CALU →	-0.530	-0.258	<.001	<.001	3	4
UCEC	OVGP1 →	+2.669	+0.150	.001	.002	3	4
GBM	ABCC3 →	-1.515	-0.166	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,854 associations by consensus.

UBE2N vs LTA4H — BRCA

Explore this scatter interactively →