UBE2N

Across TCGA cell cohorts, UBE2N RNA expression is significantly associated with the go_rna of many other GO terms, with 3,847 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible UBE2N-associated GO terms across cancer lineages are Endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA), Spindle elongation, and Endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Each is linked with UBE2N in more than 15 cancer types. Because this analysis shows association rather than direction, both UBE2N-to-partner and partner-to-UBE2N results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) grouped by UBE2N-low versus UBE2N-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (UBE2N→partner) and Y-score (partner→UBE2N) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	+0.152	+1.054	<.001	<.001	3	16
KIDNEY	Spindle elongation →	+0.193	+0.642	.004	.001	3	16
LIVER	Endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	+0.182	+0.788	<.001	.001	3	15
OVARY	DNA-templated DNA replication →	+0.112	+0.844	<.001	<.001	3	15
LIVER	rRNA 5'-end processing →	+0.182	+0.788	<.001	.001	3	15
BREAST	Negative regulation of double-strand break repair via homologous recombination →	+0.092	+0.777	<.001	.005	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,847 associations by consensus.

Endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) by UBE2N expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →