UBE2M

Across TCGA patient cohorts, UBE2M mutation is significantly associated with the immune_cell of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible UBE2M-associated genes across cancer lineages are MEP, Neutrophils, and GMP. Each is linked with UBE2M in more than 1 cancer types. Because this analysis shows association rather than direction, both UBE2M-to-partner and partner-to-UBE2M results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MEP grouped by UBE2M-low versus UBE2M-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UBE2M→partner) and Y-score (partner→UBE2M) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MEP →	+0.040	+2.839	.008	.035	3	2
UCEC	Neutrophils →	+0.019	+2.166	<.001	.021	3	2
SKCM	GMP →	+0.051	+3.806	.012	.018	3	1
UCEC	Mesangial cells →	-0.055	-2.983	.009	.036	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

MEP by UBE2M expression — UCEC

Explore this box plot interactively →