UBE2M

Across TCGA pan-cancer cohorts, UBE2M RNA differs between tumor and matched normal tissue in 16 of 18 cancer types tested, making tumor–normal expression one of UBE2M’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where UBE2M RNA is more highly expressed in tumor relative to normal tissue. In most cancer types UBE2M is over-expressed in tumor.

KIRC, HNSC, and COAD are the cancer types where UBE2M tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in UBE2M RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	IV	+0.577	<.001	12	view →
HNSC	Male	IV	+0.637	<.001	11	view →
COAD	Female	II,III,IV	+0.794	<.001	10	view →
LIHC	Female	II,III,IV	+1.460	<.001	9	view →
KIRP	All	III,IV	+0.538	<.001	9	view →
BLCA	All	All	+0.576	<.001	8	view →
LUSC	Male	All	+0.724	<.001	6	view →
BRCA	All	III,IV	+0.696	<.001	6	view →
STAD	All	II,III,IV	+0.597	.001	6	view →
UCEC	All	III,IV	+0.506	<.001	6	view →
CHOL	Male	All	+2.240	<.001	5	view →
LUAD	All	III,IV	+0.512	<.001	4	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 16 lineages.

UBE2M–KIRC

Open the KIRC breakdown →