UBE2M

Across TCGA cell cohorts, UBE2M RNA expression is significantly associated with the go_rna of many other GO terms, with 3,391 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible UBE2M-associated GO terms across cancer lineages are Negative regulation of calcium ion export across plasma membrane, Negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, and ATP metabolic process. Each is linked with UBE2M in more than 10 cancer types. Because this analysis shows association rather than direction, both UBE2M-to-partner and partner-to-UBE2M results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of calcium ion export across plasma membrane grouped by UBE2M-low versus UBE2M-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (UBE2M→partner) and Y-score (partner→UBE2M) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Negative regulation of calcium ion export across plasma membrane →	+0.064	+0.721	<.001	<.001	3	11
LARGE_INTESTINE	Negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay →	+0.127	+0.662	<.001	<.001	3	11
BREAST	ATP metabolic process →	+0.076	+0.783	<.001	<.001	3	11
PANCREAS	Termination of RNA polymerase III transcription →	+0.103	+0.883	.002	<.001	3	10
PANCREAS	Positive regulation of ubiquitin protein ligase activity →	+0.093	+0.784	.008	.004	3	10
STOMACH	Pallium development →	+0.069	+0.827	.003	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,391 associations by consensus.

Negative regulation of calcium ion export across plasma membrane by UBE2M expression — LARGE_INTESTINE

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