UBE2L2

Across TCGA patient cohorts, UBE2L2 protein abundance is significantly associated with the RNA expression of many other genes, with 978 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible UBE2L2-associated genes across cancer lineages are ZDHHC20P1, LYPD8, and ITPRIP. Each is linked with UBE2L2 in more than 1 cancer types. Because this analysis shows association rather than direction, both UBE2L2-to-partner and partner-to-UBE2L2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, UBE2L2 versus ZDHHC20P1 in BRCA, with a Pearson correlation of -0.45.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UBE2L2→partner) and Y-score (partner→UBE2L2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ZDHHC20P1 →	-0.605	-0.490	.002	.003	3	2
CCRCC	LYPD8 →	-0.353	-0.528	.001	.001	3	2
HNSC	ITPRIP →	-0.939	-0.762	.006	.009	3	2
BRCA	OR9H1P →	-0.120	-0.550	<.001	<.001	3	2
UCEC	ETFB →	-0.391	-0.517	.002	.004	3	1
UCEC	SIGLEC5 →	-0.136	-0.392	.004	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 978 associations by consensus.

UBE2L2 vs ZDHHC20P1 — BRCA

Explore this scatter interactively →