UBE2K

Across TCGA patient cohorts, UBE2K mutation is significantly associated with the RNA expression of many other genes, with 864 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible UBE2K-associated genes across cancer lineages are MTATP6P29, LINC01943, and RN7SL474P. Each is linked with UBE2K in more than 1 cancer types. Because this analysis shows association rather than direction, both UBE2K-to-partner and partner-to-UBE2K results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MTATP6P29 grouped by UBE2K-low versus UBE2K-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UBE2K→partner) and Y-score (partner→UBE2K) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MTATP6P29 →	+0.163	+2.433	.008	.009	3	2
UCEC	LINC01943 →	+0.495	+2.254	.001	.006	3	1
UCEC	RN7SL474P →	+0.088	+2.454	.008	.004	3	1
UCEC	MIR3132 →	+0.457	+2.045	<.001	.005	3	1
UCEC	AARSD1 →	+0.523	+3.470	<.001	.002	3	1
UCEC	HIKESHIP2 →	+0.667	+3.491	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 864 associations by consensus.

MTATP6P29 by UBE2K expression — UCEC

Explore this box plot interactively →