UBE2K

Across TCGA cell cohorts, UBE2K protein abundance is significantly associated with the RNA expression of many other genes, with 4,359 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible UBE2K-associated genes across cancer lineages are ESS2, TFIP11, and DEPDC5. Each is linked with UBE2K in more than 1 cancer types. Because this analysis shows association rather than direction, both UBE2K-to-partner and partner-to-UBE2K results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, UBE2K versus ESS2 in BREAST, with a Pearson correlation of 0.62.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UBE2K→partner) and Y-score (partner→UBE2K) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	ESS2 →	+0.613	+1.255	<.001	.005	3	1
BREAST	TFIP11 →	+0.625	+1.383	.003	.001	3	1
BREAST	DEPDC5 →	+0.586	+1.445	<.001	<.001	3	1
BREAST	ASCC2 →	+0.748	+1.383	.004	.001	3	1
BREAST	TYK2 →	+0.843	+1.348	<.001	.002	3	1
BREAST	FBXL12 →	+0.594	+1.680	.002	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,359 associations by consensus.

UBE2K vs ESS2 — BREAST

Explore this scatter interactively →