UBE2H

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, UBE2H mutation is significantly associated with the RNA expression of many other genes, with 79 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible UBE2H-associated genes across cancer lineages are LINC02706, DUXAP5, and NUTF2P8. Each is linked with UBE2H in more than 1 cancer types. Because this analysis shows association rather than direction, both UBE2H-to-partner and partner-to-UBE2H results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UBE2H→partner) and Y-score (partner→UBE2H) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLCALINC02706 →+0.159+7.632<.001<.00131
BLCADUXAP5 →+0.094+5.899<.001.00231
UCECNUTF2P8 →+0.128+3.175<.001.00231
UCECSTMN1P1 →+0.455+3.332.003.00531
UCECRNA5SP411 →+1.040+2.656.005.00331
UCECRNA5SP412 →+0.725+2.704<.001.00431
Each partner links to its Q-omics profile. Showing the 6 strongest of 79 associations by consensus.

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