Across TCGA pan-cancer cohorts, UBE2H RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated UBE2H data layer compared with 1 for mutation status and 7 for mass-spec protein.
The strongest signal is observed in pancreatic adenocarcinoma (PAAD), where higher UBE2H RNA is associated with worse overall survival. In most high-consensus cancer types, elevated UBE2H expression acts as an unfavorable survival marker, although some lineages such as BRCA and SKCM show a favorable association.
PAAD, HNSC, and COAD are the cancer types where UBE2H RNA most reproducibly stratifies survival.
RNA survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.