Across TCGA patient cohorts, UBE2H mutation is significantly associated with the total protein of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible UBE2H-associated genes across cancer lineages are JNK2, Caspase-8, and C-Raf. Each is linked with UBE2H in more than 1 cancer types. Because this analysis shows association rather than direction, both UBE2H-to-partner and partner-to-UBE2H results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UBE2H→partner) and Y-score (partner→UBE2H) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	JNK2 →	+0.215	+2.817	.049	.036	3	1
UCEC	Caspase-8 →	-0.328	-3.169	.017	.020	3	1
UCEC	C-Raf →	+0.235	+3.169	.002	.020	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Exploration

UBE2H survival (RNA) · tumor vs normal (RNA) · all UBE2H data types