Across TCGA patient cohorts, UBE2G2 mutation is significantly associated with the RNA expression of many other genes, with 47 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible UBE2G2-associated genes across cancer lineages are RNU6-451P, HSPE1-MOB4, and RBM48P1. Each is linked with UBE2G2 in more than 1 cancer types. Because this analysis shows association rather than direction, both UBE2G2-to-partner and partner-to-UBE2G2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UBE2G2→partner) and Y-score (partner→UBE2G2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU6-451P →	+0.717	+3.386	<.001	.008	3	2
UCEC	HSPE1-MOB4 →	+0.251	+3.799	.001	.003	3	1
COAD	RBM48P1 →	+0.081	+5.516	<.001	.004	3	1
COAD	RNA5SP169 →	+0.575	+7.734	<.001	<.001	3	1
COAD	RDM1P2 →	+0.110	+6.122	<.001	.002	3	1
UCEC	MIR6859-4 →	+0.505	+3.278	.004	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 47 associations by consensus.

Exploration

UBE2G2 survival (RNA) · tumor vs normal (RNA) · all UBE2G2 data types