UBE2G1

Across TCGA pan-cancer cohorts, UBE2G1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated UBE2G1 data layer compared with 25 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher UBE2G1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated UBE2G1 expression acts as an unfavorable survival marker, although some lineages such as CCRCC and HNSC show a favorable association.

CCRCC, HNSC, and UCEC are the cancer types where UBE2G1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Tertile	IV	0.948	0.174	.024	16	view →
HNSC	DFS	Tertile	II,III,IV	0.782	0.552	.023	16	view →
UCEC	DFS	Tertile	II,III,IV	0.919	0.490	.025	10	view →
PDAC	DFS	Median	II,III,IV	0.519	0.288	.004	9	view →
LSCC	DFS	Quartile	All	1.000	0.901	.010	4	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

UBE2G1–CCRCC (DFS)

Open the CCRCC breakdown →