UBE2G1

Across TCGA pan-cancer cohorts, UBE2G1 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of UBE2G1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where UBE2G1 RNA is repressed in tumor relative to normal tissue. In most cancer types UBE2G1 is over-expressed in tumor, although a few such as KICH and COAD show the opposite, repressed pattern.

KICH, LUSC, and CHOL are the cancer types where UBE2G1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in UBE2G1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	Female	II,III,IV	−1.107	<.001	7	view →
LUSC	Male	II,III,IV	+0.845	<.001	6	view →
CHOL	Male	All	+1.325	<.001	5	view →
COAD	All	All	−0.391	<.001	5	view →
LUAD	Male	II,III,IV	+0.576	.001	4	view →
KIRC	Male	III,IV	−0.290	.021	4	view →
HNSC	All	All	+0.286	.009	4	view →
READ	Female	All	−0.707	<.001	3	view →
LIHC	All	II,III,IV	+0.363	.017	2	view →
PRAD	All	All	+0.269	.025	2	view →
THCA	All	All	−0.177	.049	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

UBE2G1–KICH

Open the KICH breakdown →