UBE2F

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, UBE2F mutation is significantly associated with the total protein of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible UBE2F-associated genes across cancer lineages are Notch1, p70-S6K_pT389, and PDCD4. Each is linked with UBE2F in more than 1 cancer types. Because this analysis shows association rather than direction, both UBE2F-to-partner and partner-to-UBE2F results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UBE2F→partner) and Y-score (partner→UBE2F) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECNotch1 →+0.190+3.000.019.03721
UCECp70-S6K_pT389 →-0.224-3.000.042.03712
UCECPDCD4 →-0.790-3.000.003.03721
Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Exploration