UBE2E2

Across TCGA patient cohorts, UBE2E2 mutation is significantly associated with the RNA expression of many other genes, with 1,053 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible UBE2E2-associated genes across cancer lineages are DUTP5, COX5BP8, and OR9Q2. Each is linked with UBE2E2 in more than 1 cancer types. Because this analysis shows association rather than direction, both UBE2E2-to-partner and partner-to-UBE2E2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DUTP5 grouped by UBE2E2-low versus UBE2E2-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UBE2E2→partner) and Y-score (partner→UBE2E2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	DUTP5 →	+0.257	+4.271	.001	.003	3	2
COAD	COX5BP8 →	+0.253	+4.308	<.001	.009	3	2
COAD	OR9Q2 →	+0.057	+5.136	<.001	.002	3	1
COAD	MIR147A →	+0.512	+4.308	<.001	.009	3	1
COAD	TRAJ40 →	+1.027	+3.792	<.001	.007	3	1
COAD	TXNL4AP1 →	+0.212	+3.951	.002	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,053 associations by consensus.

DUTP5 by UBE2E2 expression — COAD

Explore this box plot interactively →