UBE2E1

Across TCGA patient cohorts, UBE2E1 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,826 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible UBE2E1-associated proteins across cancer lineages are THUMPD3, MRPL21, and ARHGEF10L. Each is linked with UBE2E1 in more than 3 cancer types. Because this analysis shows association rather than direction, both UBE2E1-to-partner and partner-to-UBE2E1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, UBE2E1 versus THUMPD3 in LSCC, with a Pearson correlation of 0.44.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (UBE2E1→partner) and Y-score (partner→UBE2E1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	THUMPD3 →	+0.292	+0.340	.001	.001	3	4
BRCA	MRPL21 →	-0.255	-0.524	<.001	<.001	3	4
LSCC	ARHGEF10L →	-0.314	-0.332	<.001	<.001	3	4
OV	VGLL4_S58 →	+1.261	+0.602	<.001	.001	3	4
LSCC	VGLL4 →	+0.387	+0.389	<.001	.001	3	4
CCRCC	ENAH →	+0.463	+0.246	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,826 associations by consensus.

UBE2E1 vs THUMPD3 — LSCC

Explore this scatter interactively →