UBE2E1

Across TCGA pan-cancer cohorts, UBE2E1 RNA is linked to patient survival in 29 of 34 cancer types, making it the most broadly survival-associated UBE2E1 data layer compared with 1 for mutation status.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where higher UBE2E1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated UBE2E1 expression acts as an unfavorable survival marker, although some lineages such as UVM and OV show a favorable association.

LIHC, ACC, and SARC are the cancer types where UBE2E1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LIHC	OS	Median	All	0.589	0.783	<.001	109	view →
ACC	DFS	Median	All	0.200	0.709	<.001	78	view →
SARC	DFS	Median	All	0.256	0.436	<.001	37	view →
KICH	DFS	Median	II,III,IV	0.588	0.920	.007	31	view →
UVM	OS	Median	II,III,IV	0.881	0.546	.003	24	view →
OV	OS	Tertile	III,IV	0.892	0.781	.017	18	view →
SCLC	OS	Quartile	All	0.643	0.848	.016	16	view →
SKCM	DFS	Quartile	III,IV	0.325	0.767	<.001	16	view →
CHOL	DFS	Tertile	All	0.732	0.104	.016	15	view →
MESO	OS	Quartile	All	0.214	0.416	.018	14	view →
UCS	DFS	Tertile	IV	0.875	0.323	.024	12	view →
HNSC	DFS	Median	All	0.556	0.645	.015	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 29 lineages.

UBE2E1–LIHC (OS)

Open the LIHC breakdown →