UBE2E1

Across TCGA patient cohorts, UBE2E1 mutation is significantly associated with the RNA expression of many other genes, with 3,322 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible UBE2E1-associated genes across cancer lineages are MIR615, GPR32, and RNU1-17P. Each is linked with UBE2E1 in more than 1 cancer types. Because this analysis shows association rather than direction, both UBE2E1-to-partner and partner-to-UBE2E1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR615 grouped by UBE2E1-low versus UBE2E1-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UBE2E1→partner) and Y-score (partner→UBE2E1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	MIR615 →	+1.002	+5.693	<.001	.003	3	2
CESC	GPR32 →	+0.048	+4.527	.003	.001	3	2
CESC	RNU1-17P →	+0.346	+4.688	<.001	.001	3	2
UCEC	ELMO2P1 →	+0.212	+2.209	<.001	.002	3	2
UCEC	MIR518F →	+0.357	+2.500	.001	.004	3	2
UCEC	BTBD10 →	+0.615	+3.732	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,322 associations by consensus.

MIR615 by UBE2E1 expression — COAD

Explore this box plot interactively →