UBE2E1

Across TCGA cell cohorts, UBE2E1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,148 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible UBE2E1-associated GO terms across cancer lineages are tRNA 3'-terminal CCA addition, Mitochondrial tRNA 3'-end processing, and tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation. Each is linked with UBE2E1 in more than 12 cancer types. Because this analysis shows association rather than direction, both UBE2E1-to-partner and partner-to-UBE2E1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, tRNA 3'-terminal CCA addition grouped by UBE2E1-low versus UBE2E1-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (UBE2E1→partner) and Y-score (partner→UBE2E1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	tRNA 3'-terminal CCA addition →	+0.112	+0.817	.002	.001	3	13
CNS	Mitochondrial tRNA 3'-end processing →	+0.112	+0.810	<.001	<.001	3	12
OVARY	tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation →	+0.100	+0.597	.001	.005	3	11
LUNG_SCLC	Protein localization to early endosome →	+0.164	+0.701	.001	.005	3	9
URINARY_TRACT	Centromeric sister chromatid cohesion →	+0.131	+0.818	<.001	<.001	3	9
STOMACH	Body fluid secretion →	-0.163	-1.677	<.001	.008	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,148 associations by consensus.

tRNA 3'-terminal CCA addition by UBE2E1 expression — KIDNEY

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