UBE2E1

Across TCGA cell cohorts, UBE2E1 protein abundance is significantly associated with the go_rna of many other GO terms, with 788 significant associations in total. URINARY_TRACT shows the largest number of these associations.

The most reproducible UBE2E1-associated GO terms across cancer lineages are Glutathione biosynthetic process, Intracellular sodium ion homeostasis, and Regulation of platelet aggregation. Each is linked with UBE2E1 in more than 3 cancer types. Because this analysis shows association rather than direction, both UBE2E1-to-partner and partner-to-UBE2E1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Glutathione biosynthetic process grouped by UBE2E1-low versus UBE2E1-high in LARGE_INTESTINE.

protein abundance associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (UBE2E1→partner) and Y-score (partner→UBE2E1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Glutathione biosynthetic process →	-0.147	-1.277	.005	.004	3	3
LARGE_INTESTINE	Intracellular sodium ion homeostasis →	-0.233	-1.258	.001	<.001	3	3
BLOOD_Myeloma	Regulation of platelet aggregation →	-0.115	-0.835	.005	.008	3	3
LUNG_NSCLC_LUAD	Phagocytosis, engulfment →	-0.163	-2.328	<.001	.002	3	3
LUNG_NSCLC_LUAD	Positive regulation of protein serine/threonine kinase activity →	-0.087	-1.864	<.001	.001	3	3
OESOPHAGUS	Positive regulation of calcium ion import across plasma membrane →	+0.126	+1.084	.005	.007	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 788 associations by consensus.

Glutathione biosynthetic process by UBE2E1 expression — LARGE_INTESTINE

Explore this box plot interactively →