UBE2D4

Across TCGA patient cohorts, UBE2D4 mutation is significantly associated with the RNA expression of many other genes, with 1,451 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible UBE2D4-associated genes across cancer lineages are RNA5SP411, RNA5SP408, and RNA5SP416. Each is linked with UBE2D4 in more than 1 cancer types. Because this analysis shows association rather than direction, both UBE2D4-to-partner and partner-to-UBE2D4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP411 grouped by UBE2D4-low versus UBE2D4-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UBE2D4→partner) and Y-score (partner→UBE2D4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP411 →	+0.956	+1.808	<.001	.007	3	2
UCEC	RNA5SP408 →	+0.314	+2.602	<.001	.002	3	2
UCEC	RNA5SP416 →	+0.565	+2.331	<.001	.001	3	2
UCEC	RNA5SP420 →	+0.602	+2.074	<.001	.004	3	2
LGG	RNU6-99P →	+0.248	+7.977	<.001	.007	3	1
LGG	USP9YP10 →	+0.049	+7.977	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,451 associations by consensus.

RNA5SP411 by UBE2D4 expression — UCEC

Explore this box plot interactively →