UBE2D3

Across TCGA patient cohorts, UBE2D3 protein abundance is significantly associated with the RNA expression of many other genes, with 1,831 significant associations in total. GBM shows the largest number of these associations.

The most reproducible UBE2D3-associated genes across cancer lineages are NKX2-3, NUP93, and SPAG1. Each is linked with UBE2D3 in more than 1 cancer types. Because this analysis shows association rather than direction, both UBE2D3-to-partner and partner-to-UBE2D3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, UBE2D3 versus NKX2-3 in COAD, with a Pearson correlation of -0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UBE2D3→partner) and Y-score (partner→UBE2D3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	NKX2-3 →	-0.526	-0.579	.003	.001	3	2
COAD	NUP93 →	+0.638	+0.713	.001	.001	3	1
COAD	SPAG1 →	-0.679	-0.719	.004	.001	3	1
COAD	LHB →	+0.315	+0.703	.004	.003	3	1
COAD	SNX4 →	-0.358	-0.624	.006	.004	3	1
COAD	ATP6V1B1 →	+0.053	+0.878	.005	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,831 associations by consensus.

UBE2D3 vs NKX2-3 — COAD

Explore this scatter interactively →