UBE2D3

Across TCGA patient cohorts, UBE2D3 mutation is significantly associated with the RNA expression of many other genes, with 3,156 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible UBE2D3-associated genes across cancer lineages are LINC01072, FGF21, and VSIG4. Each is linked with UBE2D3 in more than 2 cancer types. Because this analysis shows association rather than direction, both UBE2D3-to-partner and partner-to-UBE2D3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC01072 grouped by UBE2D3-low versus UBE2D3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UBE2D3→partner) and Y-score (partner→UBE2D3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	LINC01072 →	+0.105	+1.903	.001	.009	3	3
UCEC	FGF21 →	+0.520	+1.983	<.001	.003	3	2
UCEC	VSIG4 →	+1.007	+2.087	<.001	.005	3	2
BRCA	RNU6-1311P →	+0.476	+5.721	<.001	.003	3	2
CESC	RN7SL97P →	+0.100	+4.144	<.001	.001	3	2
UCEC	FCGR1CP →	+0.518	+1.979	<.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,156 associations by consensus.

LINC01072 by UBE2D3 expression — UCEC

Explore this box plot interactively →