UBE2D3

Across TCGA cell cohorts, UBE2D3 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,269 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible UBE2D3-associated GO terms across cancer lineages are Box C/D sno(s)RNA metabolic process, Box C/D sno(s)RNA processing, and Box C/D sno(s)RNA 3'-end processing. Each is linked with UBE2D3 in more than 12 cancer types. Because this analysis shows association rather than direction, both UBE2D3-to-partner and partner-to-UBE2D3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Box C/D sno(s)RNA metabolic process grouped by UBE2D3-low versus UBE2D3-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (UBE2D3→partner) and Y-score (partner→UBE2D3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Box C/D sno(s)RNA metabolic process →	+0.157	+0.510	.002	.004	2	13
LUNG_SCLC	Box C/D sno(s)RNA processing →	+0.157	+0.510	.002	.004	2	13
LUNG_SCLC	Box C/D sno(s)RNA 3'-end processing →	+0.157	+0.510	.002	.004	2	13
BLOOD_Lymphoma	Regulation of chromosome condensation →	+0.138	+0.622	.001	.008	3	11
LARGE_INTESTINE	DNA alkylation repair →	+0.077	+0.426	<.001	<.001	3	11
PANCREAS	CAAX-box protein maturation →	+0.116	+0.575	.001	.002	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,269 associations by consensus.

Box C/D sno(s)RNA metabolic process by UBE2D3 expression — LUNG_SCLC

Explore this box plot interactively →