UBE2D2

Across TCGA patient cohorts, UBE2D2 mutation is significantly associated with the RNA expression of many other genes, with 1,443 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible UBE2D2-associated genes across cancer lineages are LINC00448, SMIM28, and RPP40P1. Each is linked with UBE2D2 in more than 1 cancer types. Because this analysis shows association rather than direction, both UBE2D2-to-partner and partner-to-UBE2D2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC00448 grouped by UBE2D2-low versus UBE2D2-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UBE2D2→partner) and Y-score (partner→UBE2D2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	LINC00448 →	+0.043	+6.164	<.001	<.001	3	2
UCEC	SMIM28 →	+0.413	+2.344	<.001	.003	3	2
BRCA	RPP40P1 →	+0.118	+7.731	<.001	.009	3	2
UCEC	RNU6-728P →	+0.158	+3.335	<.001	.004	3	2
CESC	PDILT →	+0.029	+5.060	<.001	.001	3	1
CESC	RNU6-336P →	+0.220	+4.539	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,443 associations by consensus.

LINC00448 by UBE2D2 expression — CESC

Explore this box plot interactively →