UBE2D1

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, UBE2D1 protein abundance is significantly associated with the RNA expression of many other genes, with 3,571 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible UBE2D1-associated genes across cancer lineages are MIR646, RN7SL834P, and INTS9. Each is linked with UBE2D1 in more than 1 cancer types. Because this analysis shows association rather than direction, both UBE2D1-to-partner and partner-to-UBE2D1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, UBE2D1 versus MIR646 in BRCA, with a Pearson correlation of -0.74.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UBE2D1→partner) and Y-score (partner→UBE2D1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCAMIR646 →-2.021-1.668<.001.00532
OVRN7SL834P →-1.619-0.644<.001.00232
LSCCINTS9 →+0.563+0.783.003.00532
LSCCMBLAC2 →+0.637+0.878.001.00332
LSCCCXCR2 →-1.365-0.862<.001<.00132
LUADRNA5SP195 →+0.770+0.605.001.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,571 associations by consensus.

UBE2D1 vs MIR646 — BRCA

Per-sample scatter of UBE2D1 vs MIR646 in BRCA (Pearson r = -0.74).

Explore this scatter interactively →

Exploration