UBE2D1

Across TCGA pan-cancer cohorts, UBE2D1 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated UBE2D1 data layer compared with 4 for mutation status and 2 for mass-spec protein.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where higher UBE2D1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated UBE2D1 expression acts as an unfavorable survival marker, although some lineages such as COAD and SKCM show a favorable association.

LIHC, ACC, and KIRP are the cancer types where UBE2D1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LIHC	OS	Median	All	0.612	0.763	<.001	61	view →
ACC	DFS	Median	II,III,IV	0.165	0.631	<.001	39	view →
KIRP	OS	Quartile	All	0.884	0.976	.006	31	view →
PAAD	OS	Median	All	0.280	0.486	.005	26	view →
COAD	OS	Median	All	0.934	0.796	.001	26	view →
STAD	DFS	Median	III,IV	0.335	0.573	.016	25	view →
SKCM	OS	Quartile	All	0.495	0.285	.001	20	view →
SCLC	OS	Quartile	All	0.439	1.000	.018	18	view →
LUAD	OS	Median	All	0.260	0.485	.002	18	view →
UCS	OS	Tertile	II,III,IV	0.683	0.294	.018	16	view →
UCEC	DFS	Median	III,IV	0.859	0.728	.004	14	view →
UVM	DFS	Quartile	III,IV	0.235	0.792	.016	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

UBE2D1–LIHC (OS)

Open the LIHC breakdown →