UBE2D1

Across TCGA cell cohorts, UBE2D1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,563 significant associations in total. BONE shows the largest number of these associations.

The most reproducible UBE2D1-associated GO terms across cancer lineages are Regulation of protein ubiquitination, Golgi organization, and Positive regulation of mitochondrial ATP synthesis coupled electron transport. Each is linked with UBE2D1 in more than 10 cancer types. Because this analysis shows association rather than direction, both UBE2D1-to-partner and partner-to-UBE2D1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of protein ubiquitination grouped by UBE2D1-low versus UBE2D1-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (UBE2D1→partner) and Y-score (partner→UBE2D1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Regulation of protein ubiquitination →	+0.063	+0.638	<.001	<.001	3	11
STOMACH	Golgi organization →	+0.066	+0.556	.009	.007	3	10
OESOPHAGUS	Positive regulation of mitochondrial ATP synthesis coupled electron transport →	+0.137	+0.896	.001	.005	3	10
UPPER_AERODIGESTIVE_TRACT	Sphingomyelin biosynthetic process →	+0.090	+0.690	.001	.005	3	9
BONE	Phospholipid dephosphorylation →	+0.063	+0.593	.009	.007	3	9
STOMACH	Vesicle coating →	+0.091	+0.731	<.001	.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,563 associations by consensus.

Regulation of protein ubiquitination by UBE2D1 expression — LIVER

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