UBE2C

Across TCGA cell cohorts, UBE2C protein abundance is significantly associated with the RNA expression of many other genes, with 1,895 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible UBE2C-associated genes across cancer lineages are HNRNPA1L2, CSNK1G2, and KIAA1522. Each is linked with UBE2C in more than 4 cancer types. Because this analysis shows association rather than direction, both UBE2C-to-partner and partner-to-UBE2C results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, UBE2C versus HNRNPA1L2 in LUNG_SCLC, with a Pearson correlation of 0.43.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UBE2C→partner) and Y-score (partner→UBE2C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	HNRNPA1L2 →	+0.692	+0.882	<.001	<.001	3	5
OVARY	CSNK1G2 →	+0.695	+1.482	.006	.009	3	5
OVARY	KIAA1522 →	-2.431	-1.562	.003	.008	3	5
BLOOD_Leukemia	STK4 →	+0.851	+0.997	.004	.005	3	4
CNS	STX16 →	+0.838	+1.178	<.001	.002	3	4
CNS	RTEL1 →	+0.814	+0.844	.003	.004	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,895 associations by consensus.

UBE2C vs HNRNPA1L2 — LUNG_SCLC

Explore this scatter interactively →