Across TCGA pan-cancer cohorts, UBBP2 RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated UBBP2 data layer.
The strongest signal is observed in brain lower grade glioma (LGG), where higher UBBP2 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated UBBP2 expression acts as an unfavorable survival marker, although some lineages such as CESC and SKCM show a favorable association.
LGG, KIRP, and HNSC are the cancer types where UBBP2 RNA most reproducibly stratifies survival.
RNA survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.