UBAP2L

Across TCGA pan-cancer cohorts, UBAP2L Mutation is linked to patient survival in 5 of 34 cancer types, making it a survival-associated UBAP2L data layer compared with 26 for mass-spec protein and 6 for mass-spec protein.

The strongest signal is observed in rectum adenocarcinoma (READ), where higher UBAP2L Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated UBAP2L expression acts as an unfavorable survival marker, although some lineages such as STAD show a favorable association.

READ, LIHC, and ACC are the cancer types where UBAP2L Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
READ	OS	Median	All	0.447	0.941	<.001	39	view →
LIHC	DFS	Median	III,IV	0.108	0.363	.021	6	view →
ACC	DFS	Median	All	0.195	0.748	.003	3	view →
SKCM	DFS	Median	III,IV	0.133	0.654	.007	3	view →
STAD	DFS	Median	III,IV	1.000	0.566	.045	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

UBAP2L–READ (OS)

Open the READ breakdown →