UBAP2L

Across TCGA pan-cancer cohorts, UBAP2L mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated UBAP2L data layer compared with 26 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher UBAP2L mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated UBAP2L expression acts as an unfavorable survival marker, although some lineages such as LUAD and COAD show a favorable association.

LUAD, LSCC, and PDAC are the cancer types where UBAP2L mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Median	All	1.000	0.925	.003	34	view →
LSCC	OS	Tertile	III,IV	0.443	0.876	.024	13	view →
PDAC	DFS	Median	IV	0.214	0.785	.006	11	view →
HNSC	DFS	Tertile	IV	0.517	0.776	.014	7	view →
COAD	DFS	Median	III,IV	1.000	0.900	.049	6	view →
UCEC	DFS	Median	All	1.000	0.936	.023	6	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

UBAP2L–LUAD (OS)

Open the LUAD breakdown →