UBAC2

Across TCGA pan-cancer cohorts, UBAC2 RNA differs between tumor and matched normal tissue in 15 of 18 cancer types tested, making tumor–normal expression one of UBAC2’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where UBAC2 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types UBAC2 is over-expressed in tumor, although a few such as KICH and THCA show the opposite, repressed pattern.

KIRC, COAD, and BLCA are the cancer types where UBAC2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in UBAC2 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Female	IV	+1.071	<.001	11	view →
COAD	All	III,IV	+0.969	<.001	11	view →
BLCA	Male	III,IV	+0.951	<.001	11	view →
KIRP	All	IV	+1.422	<.001	10	view →
LIHC	Female	II,III,IV	+1.098	<.001	9	view →
KICH	Female	II,III,IV	−1.267	<.001	8	view →
STAD	Male	II,III,IV	+0.899	<.001	8	view →
LUAD	Male	II,III,IV	+0.604	<.001	7	view →
BRCA	Female	II,III,IV	+0.283	<.001	6	view →
CHOL	Male	All	+1.866	<.001	5	view →
LUSC	All	All	+0.544	<.001	5	view →
READ	All	II,III,IV	+0.697	.003	4	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 15 lineages.

UBAC2–KIRC

Open the KIRC breakdown →