UBA7

Across TCGA cell cohorts, UBA7 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,496 significant associations in total. CNS shows the largest number of these associations.

The most reproducible UBA7-associated GO terms across cancer lineages are Antigen processing and presentation of peptide antigen via MHC class I, CD8-positive, alpha-beta T cell activation, and Cytolysis in another organism. Each is linked with UBA7 in more than 17 cancer types. Because this analysis shows association rather than direction, both UBA7-to-partner and partner-to-UBA7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Antigen processing and presentation of peptide antigen via MHC class I grouped by UBA7-low versus UBA7-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (UBA7→partner) and Y-score (partner→UBA7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Antigen processing and presentation of peptide antigen via MHC class I →	+0.193	+2.120	<.001	<.001	3	18
URINARY_TRACT	CD8-positive, alpha-beta T cell activation →	+0.205	+2.798	<.001	<.001	3	17
BONE	Cytolysis in another organism →	+1.567	+2.070	<.001	<.001	3	17
BONE	Antigen processing and presentation of exogenous peptide antigen via MHC class Ib →	+0.257	+1.860	<.001	<.001	3	16
BREAST	Type II interferon-mediated signaling pathway →	+0.228	+2.028	<.001	<.001	3	16
LUNG_NSCLC_LUSC	Regulation of cytokine-mediated signaling pathway →	+0.071	+2.504	.003	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,496 associations by consensus.

Antigen processing and presentation of peptide antigen via MHC class I by UBA7 expression — BREAST

Explore this box plot interactively →