UBA6-AS1

Across TCGA pan-cancer cohorts, UBA6-AS1 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated UBA6-AS1 data layer.

The strongest signal is observed in brain lower grade glioma (LGG), where higher UBA6-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated UBA6-AS1 expression acts as an unfavorable survival marker, although some lineages such as OV and ESCA show a favorable association.

LGG, OV, and LIHC are the cancer types where UBA6-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LGG	OS	Median	All	0.750	0.869	<.001	47	view →
OV	OS	Median	IV	0.856	0.650	.010	30	view →
LIHC	DFS	Tertile	All	0.315	0.466	.002	27	view →
COAD	DFS	Quartile	II,III,IV	0.568	0.838	.002	26	view →
ESCA	DFS	Tertile	All	1.000	0.433	.006	25	view →
UCEC	DFS	Quartile	III,IV	0.908	0.773	.021	22	view →
ACC	DFS	Median	All	0.247	0.659	.001	21	view →
KIRC	OS	Median	All	0.695	0.564	.006	20	view →
UVM	OS	Median	All	0.765	1.000	.008	19	view →
KIRP	DFS	Median	IV	0.037	0.527	.004	18	view →
CESC	DFS	Median	III,IV	0.272	0.541	.030	14	view →
UCS	DFS	Tertile	IV	0.938	0.361	.024	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

UBA6-AS1–LGG (OS)

Open the LGG breakdown →